a big headache

基本解释

They know a Lehman bankruptcy would be a big headache come Monday when the credit markets freeze up.
他們知道，在信貸市場冰封之際，下周一雷曼兄弟破産的消息會給市場帶來重大沖擊。
recklessboy.blog.163.com
All of this is a big headache for the central government, which is aiming to keep property affordable for the masses.
這些對於中央政府來說是個大難題，後者的目標是將房地産維持在大多數人能夠承受的水平。
Doing so is simply a big headache -- or multiple headaches, rather, with names like multibrowser support, data marshaling, concurrency violation, server load, and custom servlets and servlet filters.
這麽做衹會帶來更大的麻煩（更確切地說，是更多的麻煩），比如多瀏覽器支持、數據封送処理、竝發沖突、服務器負載以及定制 servlet 和 servlet 過濾器。

But whatever the eventual outcome, the company could be left with a big headache.
ECONOMIST: The workers may be biting off more than they can chew
Ms. MITCHELL: This was basically a learning process for me, and it also was a big headache.
NPR: New Century's Borrowers Worry for Homes
If Mr Reinfeldt cannot secure a reliable majority in parliament, dealing with the SD could become a big headache.
ECONOMIST: The far right emerge as the big winners in Sweden’s election